Singapore-This cancer patient in need of chemotherapy can receive more personalized and effective treatment with the help of artificial intelligence, with potentially reduced side effects.

AI tools (known as Curate.AI) can prescribe patients with optimal drug doses throughout the chemotherapy process, minimizing side effects and achieving maximum results.

“Chemotherapy treatments are often given in fixed doses and are often adjusted based on the degree of side effects the patient experiences during treatment,” said Dean Ho, head of the Department of Medical Bioengineering at the National University. I am saying. Of the University of Design and Engineering in Singapore (NUS).

He said this may not have the most effective results for the patient. Instead, you can extend the length of time a patient remains responsive to treatment by examining the effectiveness of the treatment and customizing the optimal dose for them throughout the treatment cycle.

For some, these doses may be potentially lower than the high doses traditionally used, Ho said.

To prove that Curate.AI works in a real environment, the NUS team launched a clinical trial called Precise.Curate from August 2020 to April this year.

The study, conducted in collaboration with clinicians at the National University of Singapore Cancer Institute (NCIS), which is part of the National University Health System, enrolled 10 patients with advanced solid tumors, many of whom were stage 4 colons. I had rectal cancer.

Cancers of solid tumors include breast cancer, lung cancer, prostate cancer, colon cancer, bladder cancer, and kidney cancer.

Curate.AI utilizes patient clinical data, including selected drug types, doses, and cancer biomarkers, to be used to customize the optimal dose during chemotherapy. To generate.

Dr. Agata Blasiak, Head of Digital Innovation at NUS’s N.1 Institute for Health, presenter and co-author of the study, said that clinicians could then accept or reject recommended doses on a clinical basis. Said it was allowed. judgement.

Nevertheless, nearly 97% of the recommended doses were accepted, and some patients were prescribed optimal chemotherapy doses, which averaged about 20% lower than standard doses.

The trial was kept as realistic as possible to ensure that it was still viable in the actual clinical setting.

For example, some patients chose to skip chemotherapy treatment because of intolerable side effects, Dr. Blasiak said.

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