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Lalev, the Dutch drug monitoring agency, has received nearly 9,400 reports of heavy menstrual bleeding from women who have received the Pfizer/Biontek and Moderna coronavirus vaccines, the agency said on Friday.

The overwhelming majority involved Pfizer/BioNTech products, which are also the most widely used vaccines in the Netherlands, Lareb said.

On Friday, the European Medicines Agency said it recommended adding heavy menstrual bleeding to product information as a side effect of unknown frequency with the two vaccines.

According to Amsterdam-based EMA, cases of heavy menstrual bleeding have been reported after the first, second and booster doses of Comirnaty and Spikevax.

The EMA said most of the data was for cases that were considered to be non-serious and temporary, and that “menstrual disturbances in general are very common and can occur for a variety of reasons.” added.

The agency said there is no evidence to suggest that the menstrual disturbances experienced by some women have any effect on reproduction or fertility.


Lalev, meanwhile, is doing more research on the number of women experiencing menstrual disturbances before and after covid vaccination, based on data from their family doctor.

In total, authorities have reported more than 27,000 post-vaccination menstrual side effects, ranging from delays to increased or decreased bleeding to cramps.

Lalev said last year that menstrual irregularities are common and can be caused by infections, illness and stress. There is,” he added. “Vaccines can stimulate the immune system and affect hormone levels.”

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